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Radiosynthesis of Antitumor Spliceosome Modulators
A set of novel antitumor agents (the sudemycins) has recently been described that are analogs of the natural product FR901464. We report the radiosynthesis of two of these antitumor drug lead compounds, using a three step procedure: 1) ester hydrolysis, 2) Lindlar’s catalyst/tritium gas to give a (S...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3105125/ https://ncbi.nlm.nih.gov/pubmed/21531567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2011.04.008 |
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