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Impairment of the PD-1 pathway increases atherosclerotic lesion development and inflammation
OBJECTIVE: Programmed cell death-1 (PD-1) is a member of the CD28 superfamily that delivers negative signals upon interaction with its two ligands, PD-L1 or PD-L2. We studied the contribution of PD-1 pathway in regulating T cells that promote atherosclerotic lesion formation and inflammation. METHOD...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3104026/ https://ncbi.nlm.nih.gov/pubmed/21393583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.224709 |
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