PD-1 protects against inflammation and myocyte damage in T cell mediated myocarditis()

PD-1, a member of the CD28 family of immune regulatory molecules, is expressed on activated T cells, interacts with its ligands, PD-L1/B7-H1 and PD-L2/B7-DC on other cells, and delivers inhibitory signals to the T cell. Here we study the role of this pathway in modulating auto-reactive T cell respon...

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Bibliografiske detaljer
Main Authors:	Tarrio, Margarite L., Grabie, Nir, Bu, De-xiu, Sharpe, Arlene H., Lichtman, Andrew H.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2012
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3345066/ https://ncbi.nlm.nih.gov/pubmed/22491251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200389
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PD-1 protects against inflammation and myocyte damage in T cell mediated myocarditis()

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