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PD-1 protects against inflammation and myocyte damage in T cell mediated myocarditis()
PD-1, a member of the CD28 family of immune regulatory molecules, is expressed on activated T cells, interacts with its ligands, PD-L1/B7-H1 and PD-L2/B7-DC on other cells, and delivers inhibitory signals to the T cell. Here we study the role of this pathway in modulating auto-reactive T cell respon...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3345066/ https://ncbi.nlm.nih.gov/pubmed/22491251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200389 |
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