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PD-1 protects against inflammation and myocyte damage in T cell mediated myocarditis()

PD-1, a member of the CD28 family of immune regulatory molecules, is expressed on activated T cells, interacts with its ligands, PD-L1/B7-H1 and PD-L2/B7-DC on other cells, and delivers inhibitory signals to the T cell. Here we study the role of this pathway in modulating auto-reactive T cell respon...

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Bibliografiske detaljer
Main Authors: Tarrio, Margarite L., Grabie, Nir, Bu, De-xiu, Sharpe, Arlene H., Lichtman, Andrew H.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345066/
https://ncbi.nlm.nih.gov/pubmed/22491251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200389
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