In vivo stability and kinetics of absorption and disposition of 3' phosphopropyl amine oligonucleotides.
Development of oligonucleotide derivatives as therapeutic agents requires an understanding of their pharmacokinetic behavior. The in vivo disposition and stability of a prototype of such compounds are reported here. The compound studied, a relatively G-rich 38 base 3' phosphopropyl amine oligonucleo...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1992
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| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310371/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1741256/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.2.307 |
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