In vivo stability and kinetics of absorption and disposition of 3' phosphopropyl amine oligonucleotides.

Development of oligonucleotide derivatives as therapeutic agents requires an understanding of their pharmacokinetic behavior. The in vivo disposition and stability of a prototype of such compounds are reported here. The compound studied, a relatively G-rich 38 base 3' phosphopropyl amine oligonucleo...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Zendegui, J G, Vasquez, K M, Tinsley, J H, Kessler, D J, Hogan, M E
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1992
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310371/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1741256/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.2.307
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