Integrin αβ(1), α(v)β, α(6)β effectors p130Cas, Src and talin regulate carcinoma invasion and chemoresistance

Ligand engagement by integrins induces receptor clustering and formation of complexes at the integrin cytoplasmic face that controls cell signaling and cytoskeletal dynamics critical for adhesion-dependent processes. This study searches for a subset of integrin effectors that coordinates both tumor...

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Autori principali: Sansing, Hope A, Sarkeshik, Ali, Yates, John R, Patel, Vyomesh, Gutkind, J Silvio, Yamada, Kenneth M, Berrier, Allison L
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102534/
https://ncbi.nlm.nih.gov/pubmed/21291860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2011.01.109
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