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Clustering of α(5)β(1) integrins determines adhesion strength whereas α(v)β(3) and talin enable mechanotransduction

A key molecular link between cells and the extracellular matrix is the binding between fibronectin and integrins α(5)β(1) and α(v)β(3). However, the roles of these different integrins in establishing adhesion remain unclear. We tested the adhesion strength of fibronectin-integrin-cytoskeleton linkag...

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Autori principali: Roca-Cusachs, Pere, Gauthier, Nils C., del Rio, Armando, Sheetz, Michael P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752568/
https://ncbi.nlm.nih.gov/pubmed/19805288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902818106
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