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Clustering of α(5)β(1) integrins determines adhesion strength whereas α(v)β(3) and talin enable mechanotransduction

A key molecular link between cells and the extracellular matrix is the binding between fibronectin and integrins α(5)β(1) and α(v)β(3). However, the roles of these different integrins in establishing adhesion remain unclear. We tested the adhesion strength of fibronectin-integrin-cytoskeleton linkag...

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Bibliographic Details
Main Authors: Roca-Cusachs, Pere, Gauthier, Nils C., del Rio, Armando, Sheetz, Michael P.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752568/
https://ncbi.nlm.nih.gov/pubmed/19805288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902818106
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