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Clustering of α(5)β(1) integrins determines adhesion strength whereas α(v)β(3) and talin enable mechanotransduction

A key molecular link between cells and the extracellular matrix is the binding between fibronectin and integrins α(5)β(1) and α(v)β(3). However, the roles of these different integrins in establishing adhesion remain unclear. We tested the adhesion strength of fibronectin-integrin-cytoskeleton linkag...

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Detalhes bibliográficos
Main Authors: Roca-Cusachs, Pere, Gauthier, Nils C., del Rio, Armando, Sheetz, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752568/
https://ncbi.nlm.nih.gov/pubmed/19805288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902818106
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