Binding of ZO-1 to α5β1 integrins regulates the mechanical properties of α5β1–fibronectin links

Fundamental processes in cell adhesion, motility, and rigidity adaptation are regulated by integrin-mediated adhesion to the extracellular matrix (ECM). The link between the ECM component fibronectin (fn) and integrin α5β1 forms a complex with ZO-1 in cells at the edge of migrating monolayers, regul...

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Bibliographic Details
Published in:Mol Biol Cell
Main Authors: González-Tarragó, Víctor, Elosegui-Artola, Alberto, Bazellières, Elsa, Oria, Roger, Pérez-González, Carlos, Roca-Cusachs, Pere
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2017
Subjects:
Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541835/
https://ncbi.nlm.nih.gov/pubmed/28251923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-01-0006
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