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Rigidity sensing and adaptation through regulation of integrin types

Tissue rigidity regulates processes in development, cancer and wound healing. However, how cells detect rigidity, and thereby modulate their behaviour, remains unknown. Here, we show that sensing and adaptation to matrix rigidity in breast myoepithelial cells is determined by the bond dynamics of di...

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Hlavní autoři: Elosegui-Artola, Alberto, Bazellières, Elsa, Allen, Michael D., Andreu, Ion, Oria, Roger, Sunyer, Raimon, Gomm, Jennifer J., Marshall, John F., Jones, J. Louise, Trepat, Xavier, Roca-Cusachs, Pere
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031069/
https://ncbi.nlm.nih.gov/pubmed/24793358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3960
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