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Rigidity sensing and adaptation through regulation of integrin types

Tissue rigidity regulates processes in development, cancer and wound healing. However, how cells detect rigidity, and thereby modulate their behaviour, remains unknown. Here, we show that sensing and adaptation to matrix rigidity in breast myoepithelial cells is determined by the bond dynamics of di...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Elosegui-Artola, Alberto, Bazellières, Elsa, Allen, Michael D., Andreu, Ion, Oria, Roger, Sunyer, Raimon, Gomm, Jennifer J., Marshall, John F., Jones, J. Louise, Trepat, Xavier, Roca-Cusachs, Pere
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031069/
https://ncbi.nlm.nih.gov/pubmed/24793358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat3960
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