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A detailed mathematical model predicts serial engagement of IgE-FcεRI complexes can enhance Syk activation in mast cells

The term serial engagement was introduced to describe the ability of a single peptide, bound to a major histocompatibility complex molecule, to sequentially interact with T cell receptors within the contact region between a T cell and an antigen-presenting cell. In addition to ligands on surfaces, s...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Nag, Ambarish, Monine, Michael I., Blinov, Michael L., Goldstein, Byron
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102320/
https://ncbi.nlm.nih.gov/pubmed/20733205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000326
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