Comparable Population Pharmacokinetics and Pharmacodynamic Breakpoints of Cefpirome in Cystic Fibrosis Patients and Healthy Volunteers

Cystic fibrosis (CF) patients are often reported to have higher clearances and larger volumes of distribution per kilogram of total body weight (WT) for beta-lactams than healthy volunteers. As pharmacokinetic (PK) data on cefpirome from studies of CF patients are lacking, we systematically compared...

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Main Authors: Bulitta, J. B., Kinzig, M., Landersdorfer, C. B., Holzgrabe, U., Stephan, U., Sörgel, F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2011
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101446/
https://ncbi.nlm.nih.gov/pubmed/21402834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01484-10
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