Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics

Quinolone antibiotics present an attractive oral treatment option in patients with cystic fibrosis (CF). Prior studies have reported comparable clearances and volumes of distribution in patients with CF and healthy volunteers for primarily renally cleared quinolones. We aimed to provide the first ph...

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Publicado no:Pharmaceutics
Main Authors: Bulitta, Jürgen B., Jiao, Yuanyuan, Landersdorfer, Cornelia B., Sutaria, Dhruvitkumar S., Tao, Xun, Shin, Eunjeong, Höhl, Rainer, Holzgrabe, Ulrike, Stephan, Ulrich, Sörgel, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6681055/
https://ncbi.nlm.nih.gov/pubmed/31295857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11070323
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