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Population Pharmacokinetic Comparison and Pharmacodynamic Breakpoints of Ceftazidime in Cystic Fibrosis Patients and Healthy Volunteers

Despite the promising activity of ceftazidime against Pseudomonas aeruginosa and Burkholderia cepacia, there has not yet been a study that directly compared the pharmacokinetics (PK) of ceftazidime in cystic fibrosis (CF) patients and healthy volunteers by population PK methodology. We assessed the...

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Autors principals: Bulitta, J. B., Landersdorfer, C. B., Hüttner, S. J., Drusano, G. L., Kinzig, M., Holzgrabe, U., Stephan, U., Sörgel, F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826012/
https://ncbi.nlm.nih.gov/pubmed/20065059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00936-09
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