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New Semiphysiological Absorption Model To Assess the Pharmacodynamic Profile of Cefuroxime Axetil Using Nonparametric and Parametric Population Pharmacokinetics

Cefuroxime axetil is widely used to treat respiratory tract infections. We are not aware of a population pharmacokinetic (PK) model for cefuroxime axetil. Our objectives were to develop a semiphysiological population PK model and evaluate the pharmacodynamic profile for cefuroxime axetil. Twenty-fou...

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Autors principals: Bulitta, J. B., Landersdorfer, C. B., Kinzig, M., Holzgrabe, U., Sorgel, F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715586/
https://ncbi.nlm.nih.gov/pubmed/19528278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00054-09
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