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Structural context for mobilization of a human tRNA synthetase from its cytoplasmic complex
Human lysyl-tRNA synthetase is bound to the multi-tRNA synthetase complex (MSC) that maintains and regulates the aminoacylation and nuclear functions of LysRS. The p38 scaffold protein binds LysRS to the MSC and, only with the appropriate cue, mobilizes LysRS for redirection to the nucleus to intera...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100937/ https://ncbi.nlm.nih.gov/pubmed/21536907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1100224108 |
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