Uncovering of a Short Internal Peptide Activates a tRNA Synthetase Procytokine

In higher organisms, aminoacyl-tRNA synthetases developed receptor-mediated ex-translational functions that are activated by various natural mechanisms. Hydrogen-deuterium exchange combined with mass spectrometry and small-angle x-ray scattering showed that activation of the cytokine function of the...

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Bibliographic Details
Main Authors: Lee, Peter S., Zhang, Hui-Min, Marshall, Alan G., Yang, Xiang-Lei, Schimmel, Paul
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
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Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370235/
https://ncbi.nlm.nih.gov/pubmed/22549774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C112.369439
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