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New functions of tRNA synthetases beyond translation

Over the course of evolution, eukaryote aminoacyl tRNA synthetases progressively added domains and motifs that have no essential connection to aminoacylation reactions. Their accretive addition to virtually all tRNA synthetase correlates with the progressive evolution and complexity of eukaryotes. B...

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Bibliographic Details
Main Authors: Guo, Min, Yang, Xiang-Lei, Schimmel, Paul
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3042954/
https://ncbi.nlm.nih.gov/pubmed/20700144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2956
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