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Introduction of a leucine half-zipper engenders multiple high-quality crystals of a recalcitrant tRNA synthetase
Although Escherichia coli alanyl-tRNA synthetase was among the first tRNA synthetases to be sequenced and extensively studied by functional analysis, it has proved to be recalcitrant to crystallization. This challenge remained even for crystallization of the catalytic fragment. By mutationally intro...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2827346/ https://ncbi.nlm.nih.gov/pubmed/20179335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909055462 |
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