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Introduction of a leucine half-zipper engenders multiple high-quality crystals of a recalcitrant tRNA synthetase

Although Escherichia coli alanyl-tRNA synthetase was among the first tRNA synthetases to be sequenced and extensively studied by functional analysis, it has proved to be recalcitrant to crystallization. This challenge remained even for crystallization of the catalytic fragment. By mutationally intro...

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Detaylı Bibliyografya
Asıl Yazarlar: Guo, Min, Shapiro, Ryan, Schimmel, Paul, Yang, Xiang-Lei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827346/
https://ncbi.nlm.nih.gov/pubmed/20179335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909055462
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