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Introduction of a leucine half-zipper engenders multiple high-quality crystals of a recalcitrant tRNA synthetase

Although Escherichia coli alanyl-tRNA synthetase was among the first tRNA synthetases to be sequenced and extensively studied by functional analysis, it has proved to be recalcitrant to crystallization. This challenge remained even for crystallization of the catalytic fragment. By mutationally intro...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Guo, Min, Shapiro, Ryan, Schimmel, Paul, Yang, Xiang-Lei
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: International Union of Crystallography 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2827346/
https://ncbi.nlm.nih.gov/pubmed/20179335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444909055462
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