Structural Switch of Lysyl-tRNA Synthetase Between Translation and Transcription

Lysyl-tRNA synthetase (LysRS), a component of the translation apparatus, is released from the cytoplasmic multi-tRNA synthetase complex (MSC) to activate the transcription factor MITF in stimulated mast cells through undefined mechanisms. Here we show that Ser207-phosphorylation provokes a new confo...

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Detalhes bibliográficos
Main Authors: Ofir-Birin, Yifat, Fang, Pengfei, Bennett, Steven P., Zhang, Hui-Min, Wang, Jing, Rachmin, Inbal, Shapiro, Ryan, Song, Jing, Dagan, Arie, Pozo, Jorge, Kim, Sunghoon, Marshall, Alan G., Schimmel, Paul, Yang, Xiang-Lei, Nechushtan, Hovav, Razin, Ehud, Guo, Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3766370/
https://ncbi.nlm.nih.gov/pubmed/23159739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.10.010
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