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Structural Switch of Lysyl-tRNA Synthetase Between Translation and Transcription
Lysyl-tRNA synthetase (LysRS), a component of the translation apparatus, is released from the cytoplasmic multi-tRNA synthetase complex (MSC) to activate the transcription factor MITF in stimulated mast cells through undefined mechanisms. Here we show that Ser207-phosphorylation provokes a new confo...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2012
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3766370/ https://ncbi.nlm.nih.gov/pubmed/23159739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.10.010 |
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