Site-specific radical formation in DNA induced by Cu(II)-H(2)O(2) oxidizing system, using ESR, Immuno-spin trapping, LC/MS and MS/MS

Oxidative stress-related damage to the DNA macromolecule produces a multitude of lesions that are implicated in mutagenesis, carcinogenesis, reproductive cell death and aging. Many of these lesions have been studied and characterized by various techniques. Of the techniques that are available, the c...

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Détails bibliographiques
Auteurs principaux: Bhattacharjee, Suchandra, Deterding, Leesa J., Chatterjee, Saurabh, Jiang, JinJie, Ehrenshaft, Marilyn, Lardinois, Olivier, Ramirez, Dario C., Tomer, Kenneth B., Mason, Ronald P.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100166/
https://ncbi.nlm.nih.gov/pubmed/21382477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.02.034
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