Carregant...

DNA CLEAVAGE AND DETECTION OF DNA RADICALS FORMED FROM HYDRALAZINE AND COPPER (II) BY ESR AND IMMUNO-SPIN TRAPPING

Metal ion-catalyzed oxidation of hydrazine and its derivatives leads to the formation of the hydrazyl radical and subsequently to oxy-radicals in the presence of molecular oxygen. Here we have examined the role of Cu(2+)-catalyzed oxidation of hydralazine in the induction of DNA damage. Neither 5, 5...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Chem Res Toxicol
Autors principals: Sinha, Birandra K., Leinisch, Fabian, Bhattacharjee, Suchandra, Mason, Ronald P.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4890473/
https://ncbi.nlm.nih.gov/pubmed/24502259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500011m
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!