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Immuno-spin trapping analyses of DNA radicals
Immuno-spin trapping is a highly sensitive method for detecting DNA radicals in biological systems. This technique involves three main steps: (i) in situ and real-time trapping of DNA radicals with the nitrone spin trap 5,5-dimethyl-1-pyrroline-N-oxide (DMPO), thus forming DMPO–DNA nitrone adducts (...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2007
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711897/ https://ncbi.nlm.nih.gov/pubmed/17406615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2007.5 |
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