IMMUNO-SPIN TRAPPING FROM BIOCHEMISTRY TO MEDICINE: advances, challenges, and pitfalls: Focus on protein-centered radicals

BACKGROUND: Immuno-spin trapping (IST) is based on the reaction of a spin trap with a free radical to form a stable nitrone adduct, followed by the use of antibodies, rather than traditional electron paramagnetic resonance spectroscopy, to detect the nitrone adduct. IST has been successfully applied...

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Autors principals: Gomez-Mejiba, Sandra E., Zili, Zhai, Della-Vedova, Maria C., Muñoz, Marcos D., Chatterjee, Saurabh, Towner, Rheal A., Hensley, Kenneth, Floyd, Robert A., Mason, Ronald P., Ramirez, Dario C.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4078024/
https://ncbi.nlm.nih.gov/pubmed/23644035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.04.039
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