Site-specific radical formation in DNA induced by Cu(II)-H(2)O(2) oxidizing system, using ESR, Immuno-spin trapping, LC/MS and MS/MS

Oxidative stress-related damage to the DNA macromolecule produces a multitude of lesions that are implicated in mutagenesis, carcinogenesis, reproductive cell death and aging. Many of these lesions have been studied and characterized by various techniques. Of the techniques that are available, the c...

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Hlavní autoři: Bhattacharjee, Suchandra, Deterding, Leesa J., Chatterjee, Saurabh, Jiang, JinJie, Ehrenshaft, Marilyn, Lardinois, Olivier, Ramirez, Dario C., Tomer, Kenneth B., Mason, Ronald P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100166/
https://ncbi.nlm.nih.gov/pubmed/21382477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.02.034
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