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Demonstration of Physical Proximity between the N Terminus and the S4-S5 Linker of the Human ether-à-go-go-related Gene (hERG) Potassium Channel
Potassium channels encoded by the human ether-à-go-go-related gene (hERG) contribute to cardiac repolarization as a result of their characteristic gating properties. The hERG channel N terminus acts as a crucial determinant in gating. It is also known that the S4-S5 linker couples the voltage-sensin...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099720/ https://ncbi.nlm.nih.gov/pubmed/21474444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.238899 |
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