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Molecular Determinants of Interactions between the N-Terminal Domain and the Transmembrane Core That Modulate hERG K(+) Channel Gating

A conserved eag domain in the cytoplasmic amino terminus of the human ether-a-go-go-related gene (hERG) potassium channel is critical for its slow deactivation gating. Introduction of gene fragments encoding the eag domain are able to restore normal deactivation properties of channels from which mos...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fernández-Trillo, Jorge, Barros, Francisco, Machín, Angeles, Carretero, Luis, Domínguez, Pedro, de la Peña, Pilar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174182/
https://ncbi.nlm.nih.gov/pubmed/21935437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024674
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