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Molecular Determinants of Interactions between the N-Terminal Domain and the Transmembrane Core That Modulate hERG K(+) Channel Gating
A conserved eag domain in the cytoplasmic amino terminus of the human ether-a-go-go-related gene (hERG) potassium channel is critical for its slow deactivation gating. Introduction of gene fragments encoding the eag domain are able to restore normal deactivation properties of channels from which mos...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174182/ https://ncbi.nlm.nih.gov/pubmed/21935437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024674 |
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