FTY720 Analogues as Sphingosine Kinase 1 Inhibitors: ENZYME INHIBITION KINETICS, ALLOSTERISM, PROTEASOMAL DEGRADATION, AND ACTIN REARRANGEMENT IN MCF-7 BREAST CANCER CELLS

Ítems similars

• (R)-FTY720 METHYL ETHER IS A SPECIFIC SPHINGOSINE KINASE 2 INHIBITOR: EFFECT ON SPHINGOSINE KINASE 2 EXPRESSION IN HEK 293 CELLS AND ACTIN REARRANGEMENT AND SURVIVAL OF MCF-7 BREAST CANCER CELLS
  per: Lim, Keng Gat, et al.
  Publicat: (2011)
• Synthesis of (S)-FTY720 vinylphosphonate analogues and evaluation of their potential as sphingosine kinase 1 inhibitors and activators
  per: Liu, Zheng, et al.
  Publicat: (2013)
• FTY720 and (S)-FTY720 vinylphosphonate inhibit sphingosine kinase 1 and promote its proteasomal degradation in human pulmonary artery smooth muscle, breast cancer and androgen-independent prostate cancer cells
  per: Tonelli, Francesca, et al.
  Publicat: (2010)
• (S)-FTY720-Vinylphosphonate, an Analogue of the Immunosuppressive Agent FTY720, Is a Pan-antagonist of Sphingosine 1-Phosphate GPCR Signaling and Inhibits Autotaxin Activity
  per: Valentine, William J., et al.
  Publicat: (2010)
• Chiral Vinylphosphonate and Phosphonate Analogues of the Immunosuppressive Agent FTY720
  per: Lu, Xuequan, et al.
  Publicat: (2009)