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GTP Cyclohydrolase I: Purification, Characterization, and Effects of Inhibition on Nitric Oxide Synthase in Nocardia Species

GTP cyclohydrolase I (GTPCH) catalyzes the first step in pteridine biosynthesis in Nocardia sp. strain NRRL 5646. This enzyme is important in the biosynthesis of tetrahydrobiopterin (BH(4)), a reducing cofactor required for nitric oxide synthase (NOS) and other enzyme systems in this organism. GTPCH...

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Bibliografiske detaljer
Udgivet i:Appl Environ Microbiol
Main Authors: He, Aimin, Rosazza, John P. N.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309945/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14660404/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.12.7507-7513.2003
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