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GTP Cyclohydrolase I: Purification, Characterization, and Effects of Inhibition on Nitric Oxide Synthase in Nocardia Species
GTP cyclohydrolase I (GTPCH) catalyzes the first step in pteridine biosynthesis in Nocardia sp. strain NRRL 5646. This enzyme is important in the biosynthesis of tetrahydrobiopterin (BH(4)), a reducing cofactor required for nitric oxide synthase (NOS) and other enzyme systems in this organism. GTPCH...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309945/ https://ncbi.nlm.nih.gov/pubmed/14660404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.12.7507-7513.2003 |
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