Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine

Kae1 is a universally conserved ATPase and part of the essential gene set in bacteria. In archaea and eukaryotes, Kae1 is embedded within the protein kinase-containing KEOPS complex. Mutation of KEOPS subunits in yeast leads to striking telomere and transcription defects but the exact biochemical fu...

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Auteurs principaux: Mao, Daniel Y.L., Neculai, Dante, Downey, Michael, Orlicky, Stephen, Haffani, Yosr Z., Ceccarelli, Derek F., Ho, Jenny S.L., Szilard, Rachel K., Zhang, Wei, Ho, Cynthia S., Wan, Leo, Fares, Christophe, Rumpel, Sigrun, Kurinov, Igor, Arrowsmith, Cheryl H., Durocher, Daniel, Sicheri, Frank
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098719/
https://ncbi.nlm.nih.gov/pubmed/18951093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.10.002
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