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Is PrP the road to ruin?

One feature of neurodegenerative disorders is the accumulation of β-sheet-rich misfolded proteins, but how these proteins trigger cell death is not clear. Resenberger and coworkers report in this issue that the cellular prion protein can mediate neurotoxic signalling of various β-sheet-rich conforme...

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Bibliografiska uppgifter
Huvudupphovsmän: Barton, Kelly A, Caughey, Byron
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098489/
https://ncbi.nlm.nih.gov/pubmed/21593729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.129
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