LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection

The serine/threonine kinase LKB1 is a tumour suppressor that regulates cell growth, polarity, and proliferation in many different cell types. We previously demonstrated that LKB1 controls thymocyte survival via regulation of AMPK activation. In this study, we show that LKB1 was also involved in thym...

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Bibliografiske detaljer
Main Authors: Cao, Yonghao, Li, Hai, Liu, Haifeng, Zhang, Min, Hua, Zichun, Ji, Hongbin, Liu, Xiaolong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098487/
https://ncbi.nlm.nih.gov/pubmed/21487392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.116
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