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LKB1 regulates TCR-mediated PLCγ1 activation and thymocyte positive selection
The serine/threonine kinase LKB1 is a tumour suppressor that regulates cell growth, polarity, and proliferation in many different cell types. We previously demonstrated that LKB1 controls thymocyte survival via regulation of AMPK activation. In this study, we show that LKB1 was also involved in thym...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098487/ https://ncbi.nlm.nih.gov/pubmed/21487392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.116 |
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