A Deficiency of Ceramide Biosynthesis Causes Cerebellar Purkinje Cell Neurodegeneration and Lipofuscin Accumulation

Sphingolipids, lipids with a common sphingoid base (also termed long chain base) backbone, play essential cellular structural and signaling functions. Alterations of sphingolipid levels have been implicated in many diseases, including neurodegenerative disorders. However, it remains largely unclear...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Zhao, Lihong, Spassieva, Stefka D., Jucius, Thomas J., Shultz, Leonard D., Shick, H. Elizabeth, Macklin, Wendy B., Hannun, Yusuf A., Obeid, Lina M., Ackerman, Susan L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098191/
https://ncbi.nlm.nih.gov/pubmed/21625621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002063
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker