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Selective knockdown of ceramide synthases reveals complex interregulation of sphingolipid metabolism
Mammalian ceramide synthases 1 to 6 (CerS1–6) generate Cer in an acyl-CoA-dependent manner, and expression of individual CerS has been shown to enhance the synthesis of ceramides with particular acyl chain lengths. However, the contribution of each CerS to steady-state levels of specific Cer species...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2999923/ https://ncbi.nlm.nih.gov/pubmed/20940143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M009142 |
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