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Ceramide Synthase-dependent Ceramide Generation and Programmed Cell Death: INVOLVEMENT OF SALVAGE PATHWAY IN REGULATING POSTMITOCHONDRIAL EVENTS

The sphingolipid ceramide has been widely implicated in the regulation of programmed cell death or apoptosis. The accumulation of ceramide has been demonstrated in a wide variety of experimental models of apoptosis and in response to a myriad of stimuli and cellular stresses. However, the detailed m...

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Bibliografske podrobnosti
Main Authors: Mullen, Thomas D., Jenkins, Russell W., Clarke, Christopher J., Bielawski, Jacek, Hannun, Yusuf A., Obeid, Lina M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091202/
https://ncbi.nlm.nih.gov/pubmed/21388949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230870
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