Ceramide Synthase-dependent Ceramide Generation and Programmed Cell Death: INVOLVEMENT OF SALVAGE PATHWAY IN REGULATING POSTMITOCHONDRIAL EVENTS

The sphingolipid ceramide has been widely implicated in the regulation of programmed cell death or apoptosis. The accumulation of ceramide has been demonstrated in a wide variety of experimental models of apoptosis and in response to a myriad of stimuli and cellular stresses. However, the detailed m...

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Detalhes bibliográficos
Main Authors: Mullen, Thomas D., Jenkins, Russell W., Clarke, Christopher J., Bielawski, Jacek, Hannun, Yusuf A., Obeid, Lina M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091202/
https://ncbi.nlm.nih.gov/pubmed/21388949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230870
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