Ceramide Synthase-dependent Ceramide Generation and Programmed Cell Death: INVOLVEMENT OF SALVAGE PATHWAY IN REGULATING POSTMITOCHONDRIAL EVENTS

The sphingolipid ceramide has been widely implicated in the regulation of programmed cell death or apoptosis. The accumulation of ceramide has been demonstrated in a wide variety of experimental models of apoptosis and in response to a myriad of stimuli and cellular stresses. However, the detailed m...

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Dettagli Bibliografici
Autori principali: Mullen, Thomas D., Jenkins, Russell W., Clarke, Christopher J., Bielawski, Jacek, Hannun, Yusuf A., Obeid, Lina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
Soggetti:
Lipids
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3091202/
https://ncbi.nlm.nih.gov/pubmed/21388949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230870
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