Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences

BACKGROUND: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the efficacy and safety of gene therapies. Oligomerized Pool ENgineering (OPEN) is a recently developed method for engineering C...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sander, Jeffry D, Reyon, Deepak, Maeder, Morgan L, Foley, Jonathan E, Thibodeau-Beganny, Stacey, Li, Xiaohong, Regan, Maureen R, Dahlborg, Elizabeth J, Goodwin, Mathew J, Fu, Fengli, Voytas, Daniel F, Joung, J Keith, Dobbs, Drena
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2010
Pynciau:
Methodology Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098093/
https://ncbi.nlm.nih.gov/pubmed/21044337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-543
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