Rapid Mutation of Endogenous Zebrafish Genes Using Zinc Finger Nucleases Made by Oligomerized Pool ENgineering (OPEN)

BACKGROUND: Customized zinc finger nucleases (ZFNs) form the basis of a broadly applicable tool for highly efficient genome modification. ZFNs are artificial restriction endonucleases consisting of a non-specific nuclease domain fused to a zinc finger array which can be engineered to recognize speci...

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Detalhes bibliográficos
Main Authors: Foley, Jonathan E., Yeh, Jing-Ruey J., Maeder, Morgan L., Reyon, Deepak, Sander, Jeffry D., Peterson, Randall T., Joung, J. Keith
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2634973/
https://ncbi.nlm.nih.gov/pubmed/19198653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0004348
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