Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences

BACKGROUND: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the efficacy and safety of gene therapies. Oligomerized Pool ENgineering (OPEN) is a recently developed method for engineering C...

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Main Authors: Sander, Jeffry D, Reyon, Deepak, Maeder, Morgan L, Foley, Jonathan E, Thibodeau-Beganny, Stacey, Li, Xiaohong, Regan, Maureen R, Dahlborg, Elizabeth J, Goodwin, Mathew J, Fu, Fengli, Voytas, Daniel F, Joung, J Keith, Dobbs, Drena
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2010
נושאים:
Methodology Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098093/
https://ncbi.nlm.nih.gov/pubmed/21044337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-543
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