Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences

BACKGROUND: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the efficacy and safety of gene therapies. Oligomerized Pool ENgineering (OPEN) is a recently developed method for engineering C...

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Bibliografiske detaljer
Main Authors: Sander, Jeffry D, Reyon, Deepak, Maeder, Morgan L, Foley, Jonathan E, Thibodeau-Beganny, Stacey, Li, Xiaohong, Regan, Maureen R, Dahlborg, Elizabeth J, Goodwin, Mathew J, Fu, Fengli, Voytas, Daniel F, Joung, J Keith, Dobbs, Drena
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098093/
https://ncbi.nlm.nih.gov/pubmed/21044337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-543
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