Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences

BACKGROUND: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the efficacy and safety of gene therapies. Oligomerized Pool ENgineering (OPEN) is a recently developed method for engineering C...

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Główni autorzy: Sander, Jeffry D, Reyon, Deepak, Maeder, Morgan L, Foley, Jonathan E, Thibodeau-Beganny, Stacey, Li, Xiaohong, Regan, Maureen R, Dahlborg, Elizabeth J, Goodwin, Mathew J, Fu, Fengli, Voytas, Daniel F, Joung, J Keith, Dobbs, Drena
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2010
Hasła przedmiotowe:
Methodology Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098093/
https://ncbi.nlm.nih.gov/pubmed/21044337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-543
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