Spinal Phosphinositide 3-Kinase–Akt–Mammalian Target of Rapamycin Signaling Cascades in Inflammation-Induced Hyperalgesia

Phosphinositide 3-kinase (PI3K), Akt, and their downstream kinase, mammalian target of rapamycin (mTOR), are implicated in neural plasticity. The functional linkages of this signaling cascade in spinal dorsal horn and their role in inflammatory hyperalgesia have not been elucidated. In the present w...

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Detalhes bibliográficos
Main Authors: Xu, Qinghao, Fitzsimmons, Bethany, Steinauer, Joanne, Neill, Audrey O', Newton, Alexandra C., Hua, Xiao-Ying, Yaksh, Tony L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097059/
https://ncbi.nlm.nih.gov/pubmed/21307248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2139-10.2011
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