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Spinal matrix metalloproteinase 3 mediates inflammatory hyperalgesia via a TNF dependent mechanism
Matrix metalloproteinases (MMPs) have been implicated in the modulation of synaptic plasticity, glial activation and long-term potentiation in the CNS. Here we demonstrate for the first time a mechanism for the regulation of nociceptive processing by spinal MMP-3 during peripheral inflammation. We f...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3346277/ https://ncbi.nlm.nih.gov/pubmed/22056600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2011.10.019 |
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