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Role of spinal p38α and β MAPK in inflammatory hyperalgesia and spinal COX-2 expression

Pharmacological studies indicate that spinal p38 MAPK plays a role in the development of hyperalgesia. We investigated whether either the spinal isoform p38α or p38β is involved in peripheral inflammation-evoked pain state and increased expression of spinal COX-2. Using intrathecal antisense oligonu...

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Bibliografische gegevens
Hoofdauteurs: Fitzsimmons, Bethany L., Zattoni, Michela, Svensson, Camilla I., Steinauer, Joanne, Hua, Xiao-Ying, Yaksh, Tony L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877130/
https://ncbi.nlm.nih.gov/pubmed/20134354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e32833774bf
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