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Mutations that replace aromatic side chains promote aggregation of the Alzheimer’s Aβ peptide

The aggregation of polypeptides into amyloid fibrils is associated with a number of human diseases. Because these fibrils – or intermediates on the aggregation pathway – play important roles in the etiology of disease, considerable effort has been expended to understand which features of the amino a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Armstrong, Anne H., Chen, Jermont, McKoy, Angela Fortner, Hecht, Michael H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097045/
https://ncbi.nlm.nih.gov/pubmed/21513285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200268w
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